KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN3
All Species:
13.64
Human Site:
Y605
Identified Species:
21.43
UniProt:
Q6P5Z2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5Z2
NP_037487.2
889
99421
Y605
R
D
E
I
E
S
L
Y
C
E
K
R
I
L
E
Chimpanzee
Pan troglodytes
XP_001159776
886
99121
Y602
R
D
E
I
E
S
L
Y
C
E
K
R
I
L
E
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
G718
R
D
E
I
D
S
L
G
N
K
V
R
P
C
L
Dog
Lupus familis
XP_548434
951
104664
Y667
R
D
E
M
E
S
L
Y
C
E
K
R
I
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K045
878
97863
Y594
R
D
E
I
D
S
L
Y
C
E
K
R
I
L
E
Rat
Rattus norvegicus
O08874
985
112050
M704
R
D
E
V
D
S
L
M
C
E
K
R
I
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
H709
R
D
E
L
E
S
L
H
C
E
K
R
I
L
E
Chicken
Gallus gallus
XP_422357
1013
114806
M732
R
D
E
V
D
S
L
M
C
E
K
R
I
F
E
Frog
Xenopus laevis
Q7ZX15
486
56292
A257
R
V
F
T
E
D
R
A
R
F
Y
G
A
E
I
Zebra Danio
Brachydanio rerio
XP_697542
940
106140
M660
R
D
E
V
D
S
L
M
C
E
K
R
I
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
A405
R
F
E
A
S
R
A
A
F
Y
A
A
E
V
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
I468
G
G
D
L
M
F
Q
I
Q
R
A
R
K
F
D
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
M518
R
E
E
V
E
S
L
M
C
E
K
R
I
F
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
R870
N
H
D
I
E
S
A
R
A
E
K
K
V
F
L
Red Bread Mold
Neurospora crassa
P87253
1142
127954
R863
N
D
E
V
E
S
I
R
S
E
K
R
V
F
L
Conservation
Percent
Protein Identity:
100
97.7
81.5
84.2
N.A.
83.2
49.9
N.A.
64.2
48.9
26.2
52.2
N.A.
28
N.A.
29.1
41.5
Protein Similarity:
100
97.8
82.9
87.6
N.A.
88.4
63.6
N.A.
72.9
63
36.6
67.6
N.A.
41.5
N.A.
43.9
58.2
P-Site Identity:
100
100
46.6
93.3
N.A.
93.3
73.3
N.A.
86.6
73.3
13.3
73.3
N.A.
13.3
N.A.
6.6
73.3
P-Site Similarity:
100
100
60
100
N.A.
100
86.6
N.A.
100
86.6
13.3
86.6
N.A.
20
N.A.
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
27.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
43.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
14
14
7
0
14
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
60
0
0
0
0
7
0
% C
% Asp:
0
67
14
0
34
7
0
0
0
0
0
0
0
0
7
% D
% Glu:
0
7
80
0
54
0
0
0
0
74
0
0
7
7
60
% E
% Phe:
0
7
7
0
0
7
0
0
7
7
0
0
0
47
0
% F
% Gly:
7
7
0
0
0
0
0
7
0
0
0
7
0
0
0
% G
% His:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
34
0
0
7
7
0
0
0
0
60
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
7
74
7
7
0
0
% K
% Leu:
0
0
0
14
0
0
67
0
0
0
0
0
0
34
20
% L
% Met:
0
0
0
7
7
0
0
27
0
0
0
0
0
0
0
% M
% Asn:
14
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% Q
% Arg:
80
0
0
0
0
7
7
14
7
7
0
80
0
0
0
% R
% Ser:
0
0
0
0
7
80
0
0
7
0
0
0
0
0
0
% S
% Thr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% T
% Val:
0
7
0
34
0
0
0
0
0
0
7
0
14
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
27
0
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _